Associations of maternal plasma and umbilical cord plasma metabolomics profiles with birth anthropometric measures.

ABSTRACT:

Background

The metabolomics profiles of maternal plasma during pregnancy and cord plasma at birth might influence fetal growth and birth anthropometry. The objective was to examine how maternal plasma and umbilical cord plasma metabolites are associated with newborn anthropometric measures, a known predictor of future health outcomes.

Methods

Pregnant women between 24 and 28 weeks of gestation were recruited as part of a prospective cohort study. Blood samples from 413 women at enrollment and 787 infant cord blood samples were analyzed using the Biocrates AbsoluteIDQ® p180 kit. Multivariable linear regression models were used to examine associations of cord and maternal metabolites with infant anthropometry at birth.

Results

In cord blood samples from this rural cohor

SUBMITTER: Yeum D 

PROVIDER: S-EPMC12269892 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature