Transcranial Doppler goal-directed therapy after cardiac arrest (GOODYEAR): a feasibility study.

ABSTRACT:

Aim

Hypoxic Ischemic Brain Injury is a major cause of death after cardiac arrest. Identifying optimal mean arterial pressure (MAP) targets to restore brain oxygen delivery remains challenging. This study assessed the feasibility of using transcranial Doppler to guide individualised MAP management in post-cardiac arrest patients.

Methods

In this single-centre prospective feasibility study, post-cardiac arrest patients were enrolled after intensive care unit admission. After induction of targeted temperature management (TTM) and control of systemic secondary brain insults determinants, cerebral hypoperfusion was screened using transcranial Doppler. A MAP challenge was performed in patients with abnormal transcranial Doppler findings to assess cerebral vascular responsiveness t

SUBMITTER: Meunier J 

PROVIDER: S-EPMC12270008 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature