Association of physical activity, cardiorespiratory fitness, grip strength, and grip strength asymmetry with incident musculoskeletal disorders in 406,080 White adults.

ABSTRACT:

Background

Musculoskeletal disorders (MSDs) represent a significant global health burden. While physical activity (PA) and physical fitness are both thought to reduce MSD risk, their independent and joint associations with MSD incidence have not been fully explored. This study investigated the independent and combined effects of PA, cardiorespiratory fitness (CRF), grip strength (GS), and GS asymmetry on MSD incidence in a large prospective cohort.

Methods

We analyzed data from the UK Biobank cohort (2006-2023), including 406,080 participants aged 37-73 years (age = 55.7 ± 8.2 years, mean ± SD; 53.0% female) who were free of MSD at baseline and during the first 2 years of follow-up. PA, derived from self-reported data and expressed in total metabolic equivalent hours per wee

SUBMITTER: Yu Y 

PROVIDER: S-EPMC12270075 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature