Deciphering the genetic landscape of tomato leaf curl New Delhi virus: Dynamic and region-specific diversity revealed by comprehensive sequence analyses.

ABSTRACT: Tomato leaf curl New Delhi virus (ToLCNDV), a swiftly spreading bipartite begomovirus infecting ~43 plant species across Asia, Africa, and Europe, poses a major agricultural threat. This study comprehensively investigated the genetic diversity and evolutionary dynamics of ToLCNDV using a large dataset of sequences from diverse geographic regions across Asia, Africa, and Europe. Phylogenetic analysis of DNA-A (TA) and DNA-B (TB) components revealed seven major clades for each component, demonstrating regional but not host-specific clustering. Notably, TA and TB exhibited distinct geographic segregation and genetic diversity, with cognate segments often clustering separately. Extensive recombination events were detected (44 in TA and 45 in TB), involving both intra- and interspecies events.

SUBMITTER: Iqbal Z 

PROVIDER: S-EPMC12270167 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature