Brain network dynamics following induced acute stress: a neural marker of psychological vulnerability to real-life chronic stress.

ABSTRACT:

Background

Stress leads to neurobiological changes, and failure to regulate these can contribute to chronic psychiatric issues. Despite considerable research, the relationship between neural alterations in acute stress and coping with chronic stress is unclear. This longitudinal study examined whole-brain network dynamics following induced acute stress and their role in predicting chronic stress vulnerability.

Methods

Sixty military pre-deployment soldiers underwent a lab-induced stress task where subjective stress and resting-state functional magnetic resonance imaging were acquired repeatedly (before stress, after stress, and at recovery, 90 min later). Baseline depression and post-traumatic stress symptoms were assessed, and again a year later during military deployment.

SUBMITTER: Segal A 

PROVIDER: S-EPMC12270275 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature