The relationship between metabolic syndrome and environmental endocrine disruptors: A systematic review and meta-analysis.

ABSTRACT: Metabolic syndrome (MetS) is considered to be an important factor leading to an increased risk of chronic non-communicable diseases. Studies have found that exposure to environmental endocrine disruptors (EEDs) is associated with MetS, but the relationship between the two is unclear. In order to clarify the relationship between the two, a systematic review and meta-analysis were conducted to investigate their association. We searched Web of Science databases, Embase, and PubMed. We then utilized I² statistics to assess the literature heterogeneity and pooled the data using both fixed-effects model (I² < 50%) and the random effects model (I² > 50%) in accordance with the PRISMA guidelines. The results showed that exposure to perfluoroalkyl substances (PFASs)

SUBMITTER: Pan K 

PROVIDER: S-EPMC12270799 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature