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Diastolic Hyperemia-Free Ratio in Patients With Coronary Artery Disease: A Prospective Observational Study.


ABSTRACT:

Background and objectives

Diastolic hyperemia-free ratio (DFR), an alternative to fractional flow reserve (FFR) for the assessment of intermediate coronary artery stenosis, helps reduce patients' time, and inconvenience. However, the validation data for DFR and FFR are lacking. We aimed to evaluate the diagnostic accuracy of DFR and FFR and to assess the effective decision making for revascularization using their values.

Methods

Patients subjected to an invasive physiological study for intermediate coronary artery stenosis at a single center in South Korea between August 2022 and January 2024 were prospectively recruited. We evaluated the correlation between DFR and FFR measurements and the diagnostic accuracy of DFR ≤0.89 to predict FFR ≤ 0.80. We also compared the correlat

SUBMITTER: Roh JW 

PROVIDER: S-EPMC12270830 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature