Global, regional, and national burden and projections to 2050 of occupational carcinogen-attributable nasopharyngeal and laryngeal cancer: a comprehensive analysis from the GBD 2021 study.

ABSTRACT:

Background

Occupational carcinogens contribute to the burden of nasopharyngeal (NPC) and laryngeal cancer (LC), yet their global impact and long-term trends remain insufficiently explored. This study estimates the burden, temporal trends, and future projections of occupational carcinogen-attributable NPC and LC from 1990 to 2050.

Methods

Using data from Global Burden of Disease (GBD) 2021, we analyzed death and disability-adjusted life years (DALYs) across 204 countries and territories. Age-standardized death rate (ASDR), age-standardized DALYs rate, and estimated annual percentage change (EAPC) were used to assess trends. Decomposition analysis quantified the contributions of epidemiological changes, population growth, and aging. Future projections (2022-2050) were estimate

SUBMITTER: Zhang H 

PROVIDER: S-EPMC12270855 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature