Homeostatic Appetite and Hedonic Hunger 13 Years After Roux-en-Y Gastric Bypass: Potential Associations and Predictive Value in Determining Long-Term Weight Loss Outcomes.

ABSTRACT:

Introduction

The interplay between homeostatic and hedonic appetite following Roux-en-Y gastric bypass (RYGB) and their potential relevance in modulating long-term weight loss (WL) outcomes has not been properly explored.

Aim

The main aim of this analysis was to explore the association between homeostatic appetite markers and hedonic hunger 13 years post-RYGB. A secondary aim was to determine the association between homeostatic and hedonic appetite, and % total weight loss (TWL).

Methods

Hedonic hunger was measured with the Power of Food scale (food available, food present, food tasted and aggregated score). The plasma concentration of gastrointestinal (GI) hormones involved in appetite regulation was measured with validated methods, and subjective appetite ratings (h

SUBMITTER: Nymo S 

PROVIDER: S-EPMC12270954 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature