Changes in Ocular Biometry After Pharmacologic Cycloplegia and Mydriasis in Primary Angle Closure Disease.

ABSTRACT:

Introduction

The mechanism of primary angle closure disease (PACD) has been extensively investigated, while some cases remain unexplained. Hypothesizing that chronic primary ciliary block (CB) may play a role in PACD pathogenesis and the contribution could be revealed by pharmacologic cycloplegia and mydriasis, this study analyzed changes in anterior segment biometric parameters following cycloplegic intervention.

Methods

A total of 170 eyes of 170 Chinese subjects aged between 50 and 80 years were included: 90 in the primary angle closure suspect (PACS) group, 33 in the primary angle closure (PAC)/PAC glaucoma (PACG) group, and 47 in the normal control group. All participants underwent a comprehensive ophthalmic examination, and ultrasound biomicroscopy (UBM) was conducted

SUBMITTER: Ma Y 

PROVIDER: S-EPMC12270998 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature