Gut Microbial Signatures in Long COVID: Potential Biomarkers and Therapeutic Targets.

ABSTRACT:

Introduction

Following severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection, symptoms can persist for more than 12 weeks in over 10% of patients in a condition known as long coronavirus disease (COVID). Gut microbiota dysbiosis is correlated with long COVID, but the specific relationship between long COVID and the gut microbiome remains unclear. Here, we aimed to investigate connections between the gut microbiota and long COVID severity.

Methods

Fecal samples were collected from 31 patients with long COVID, 14 with COVID-19 but not long COVID, and 23 healthy controls. The mean interval between COVID-19 diagnosis and sample collection was 65.5 (range: 13.0-110.3) weeks for patients with long COVID and 74.8 (range: 50.7-110.4) weeks for positive control group

SUBMITTER: Oh S 

PROVIDER: S-EPMC12271030 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature