Triglyceride-glucose index threshold for cardiovascular mortality in hypertensive individuals - URRAH project.

ABSTRACT:

Aims

The triglyceride-glucose (TyG) index is a surrogate marker of insulin resistance (IR). Data regarding this topic is constantly increasing, however, few and heterogeneous data are available on the relationship between this index and cardiovascular mortality risk in hypertensive populations. In this context, we aimed to explore the relationship between TyG and cardiovascular mortality in a large sample of hypertensive individuals from the URRAH cohort.

Methods

A total of 12,275 hypertensive participants without previous cardiovascular events were included in this analysis. The risk of cardiovascular mortality was evaluated by the Cox regression analysis and competing risk regression analysis.

Results

During a median follow-up of 10.5 years, 2151 deaths occurred, of

SUBMITTER: D'Elia L 

PROVIDER: S-EPMC12271081 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature