Age and sex differences in outpatient antipsychotic prescriptions for schizophrenia: a claims data study.

ABSTRACT: Most studies on antipsychotic efficacy and safety, including sex differences, focus on young schizophrenia patients. However, with an aging population, the number of older schizophrenia patients is increasing. This group faces challenges due to varying treatment responses and higher risks of adverse reactions, and guidelines often lack specific recommendations due to insufficient trials. Therefore, we investigated how age and sex influence antipsychotic prescribing practices in schizophrenia using the German Pharmacoepidemiological Research Database (GePaRD). We included patients diagnosed with schizophrenia (ICD-10 code F20.X) who had been prescribed at least one antipsychotic on an outpatient basis in at least two consecutive quarters in 2020, analyzing prescription data for 49,681 patie

SUBMITTER: Ramin T 

PROVIDER: S-EPMC12271300 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature