Impact of dexamethasone therapy on mortality in critically ill patients with non-traumatic intracerebral hemorrhage: a propensity score-matched cohort study.

ABSTRACT: Non-traumatic intracerebral hemorrhage (ICH) is the most common type of hemorrhagic stroke. The therapeutic effects of dexamethasone in ICH patients remain unclear. This study aimed to examine the association of dexamethasone use with the all-cause mortality rate in critically patients with ICH. This was a retrospective cohort study based on the Medical Information Mart for Intensive Care (MIMIC-IV) database. Eligible ICH patients were selected and divided into two groups on the basis of whether they received dexamethasone treatment during their hospitalization. A 1:1 propensity score matching was applied. The relationship between dexamethasone and mortality was analyzed using the Kaplan-Meier method. LASSO regression was used to select covariates for the Cox regression model, and the prop

SUBMITTER: Lu Y 

PROVIDER: S-EPMC12271541 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature