Effects of alcohol consumption on employment and social outcomes: a Mendelian randomisation study.

ABSTRACT:

Aims

Alcohol consumption is associated with socioeconomic disadvantage, but causality is unclear. We used Mendelian randomisation (MR) to estimate the effect of alcohol consumption on socioeconomic and employment-related outcomes.

Methods

We conducted observational analyses and two-sample MR analyses using 230 775 working-age participants (aged 40+) of White British ethnicity/ancestry (54.5% male) from the UK Biobank.

Outcomes

employment status (employed vs not; employed vs sickness/disability, unemployment, retirement or caring for home/family); weekly hours worked (among employed); deprivation (Townsend Deprivation Index); highest educational attainment; and household income.

Exposures

alcohol consumption (units per week), hazardous alcohol consumption assess

SUBMITTER: Campbell DD 

PROVIDER: S-EPMC12271571 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature