Effect of trimethoprim on Calliphora stygia (Diptera: Calliphoridae) larvae growth and detection via liquid chromatography-tandem mass spectrometry.

ABSTRACT: Insects are crucial in the estimation of time-since-death of remains due to their predictable growth. Pharmaceuticals present in decomposing remains may alter insect growth and could affect postmortem interval calculations. Here we report on an investigation into the effects of trimethoprim, on the growth of Calliphora stygia (Fabricius, 1781) (Diptera; Calliphoridae) larvae, a common species of blow fly in Australia. We asked: (i) does trimethoprim influence larval growth, and (ii) can trimethoprim be detected in C. stygia larvae reared on trimethoprim? We found a significant increase in larval length in the trimethoprim-exposed group relative to the control group as accumulated degree hours increased. By mid-late experiment (~3,000 accumulative degree hours), larvae exposed to trimethopr

SUBMITTER: McIntyre DB 

PROVIDER: S-EPMC12271731 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature