Incidence of Human Metapneumovirus Among Older Adults in 10 High-Income Countries: A Systematic Literature Review, Meta-analysis, and Modeling Study.

ABSTRACT:

Background

The epidemiologic landscape for human metapneumovirus (hMPV), a respiratory pathogen, is poorly characterized, particularly among older adults.

Methods

Leveraging the latest estimates of lower respiratory infection (LRI) incidence from the Global Burden of Disease Study 2021 and meta-analyzed findings from a systematic literature review, we quantified the incidence of LRI with hMPV in 10 high-income locations among older adults in the most recent prepandemic year (2019): Canada, Chile, France, Germany, New Zealand, Netherlands, Italy, Spain, United Kingdom, and United States.

Results

The systematic literature review identified 21 studies with data on the percentage of LRI episodes associated with hMPV in adults aged ≥60 years in the targeted locations. Comb

SUBMITTER: Lei J 

PROVIDER: S-EPMC12272053 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature