Preserving spatial and quantitative information in unpaired biomedical image-to-image translation.

ABSTRACT: Analysis of biological samples often requires integrating diverse imaging modalities to gain a comprehensive understanding. While supervised biomedical image translation methods have shown success in synthesizing images across different modalities, they require paired data, which are often impractical to obtain due to challenges in data alignment and sample preparation. Unpaired methods, while not requiring paired data, struggle to preserve the precise spatial and quantitative information essential for accurate analysis. To address these challenges, we introduce STABLE (spatial and quantitative information preserving biomedical image translation), an unpaired image-to-image translation method that emphasizes the preservation of spatial and quantitative information by enforcing information

SUBMITTER: You JY 

PROVIDER: S-EPMC12272260 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature