Systematic cross-species comparison of prefrontal cortex functional networks targeted via transcranial magnetic stimulation.

ABSTRACT: Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation method that safely modulates neural activity in vivo. Its precision in targeting specific brain networks makes TMS invaluable in diverse clinical applications. For example, TMS is used to treat depression by targeting prefrontal brain networks and their connection to other brain regions. Despite its widespread use, however, the underlying neural mechanisms of TMS are not completely understood. Non-human primates (NHPs) offer an ideal model to study TMS mechanisms through invasive electrophysiological recordings. As such, bridging the gap between NHP experiments and human applications is imperative to ensure translational relevance. Here, we systematically compare the TMS-targeted functional networks in the prefront

SUBMITTER: Berger T 

PROVIDER: S-EPMC12272263 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature