Novel Tracheal Parameters Based on Quantitative Computed Tomography Assessment Reflecting Pulmonary Function and Eosinophilia in Patients With Asthma Who Demonstrate Persistent Airflow Obstruction: A Retrospective Observational Cross-Sectional Study.

ABSTRACT:

Background and aims

This study aimed to clarify relationships between tracheal parameters based on quantitative computed tomography (CT) assessment and clinical features in patients with chronic obstructive airway disease (COPD), asthma and COPD overlap (ACO), and asthma with persistent airflow obstruction.

Methods

Patients with obstructive airway diseases who underwent pulmonary function tests, chest CT, and laboratory examinations were categorized into COPD, ACO, and asthma with persistent airflow obstruction (obstructive-asthma) groups. The tracheal index (included in the saber-sheath trachea definition) and novel tracheal parameters measured at the same axial CT level, 1 cm above the aortic arch, as defined for the saber-sheath trachea, were analyzed.

Results

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SUBMITTER: Kitaguchi Y 

PROVIDER: S-EPMC12272299 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature