Eradication of MRSA biofilms using amphiphilic cationic coumarin derivatives.

ABSTRACT: Amphiphilic coumarin derivatives have demonstrated potent antibiofilm activity against established methicillin-resistant Staphylococcus aureus (MRSA) biofilms. Scanning electron microscopy (SEM) revealed morphological changes to bacterial cells and eradication of extracellular matrix from established MRSA biofilms when treated with 7-benzyloxy coumarin derivatives.

SUBMITTER: Nitschke SO 

PROVIDER: S-EPMC12272568 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature