Validation of the Proposed Definition for Complicated Coagulase-negative Staphylococcal Bacteremia.

ABSTRACT:

Background

A new definition for complicated coagulase-negative staphylococcal (CoNS) bacteremia was recently proposed. The aim of this study was to identify predictors of mortality in patients with CoNS bacteremia and evaluate the proposed definition of complicated bacteremia.

Methods

This retrospective study was conducted at the Lausanne University Hospital, Switzerland (2015-2023) and included adult patients with CoNS bacteremia.

Results

During the study period, 326 episodes of CoNS bacteremia were included, with 250 (77%) episodes involving Staphylococcus epidermidis. Most infections were catheter-related bacteremias (233 episodes; 68%). Based on the proposed definition, 195 (60%) episodes had complicated disease. The overall 30-day mortality was 9% (29 episodes).

SUBMITTER: Papadimitriou-Olivgeris M 

PROVIDER: S-EPMC12272850 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature