Drug resistance mutations among people living with HIV and ART failure in Bangladesh: a cross-sectional study.

ABSTRACT:

Background

While maintaining a low HIV prevalence among the general population, Bangladesh is among the few countries in the Asia-Pacific region where the incidence of people living with HIV (PLWH) continues to increase. The National Anti-Retroviral Therapy Program still relies on a 'Test and Treat' strategy and faces challenges in treating drug-resistant HIV. This study aims to assess the HIV viral load and drug resistance mutations among key populations (KPs) under anti-retroviral therapy (ART) in Bangladesh.

Methods

A total of 110 KPs from 20 drop-in-centers across 11 districts in Bangladesh were enrolled from March 2019 to November 2020 for viral load (VL) testing using Xpert® HIV-1 Viral Load kits. Samples with high VL (≥1000 copies/mL) underwent pol gene sequencing to

SUBMITTER: Rahman S 

PROVIDER: S-EPMC12272934 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature