Association between the red blood cell distribution width-platelet ratio and the risk of in-hospital mortality in patients with alcoholic liver cirrhosis (with or without severe liver disease): a retrospective cohort study based on the MIMIC-IV database.

ABSTRACT:

Purpose

The incidence of alcoholic liver cirrhosis (ALC) has been gradually rising in recent years, with a poor prognosis. This study aimed to investigate the association between the red blood cell distribution width-platelet ratio (RPR) and the in-hospital mortality risk among patients with ALC.

Methods

A total of 1424 patients with ALC were extracted from the Medical Information Mart for Intensive Care IV for carrying out this retrospective study. Based on the value of RPR, the included patients were divided into quartiles. The association between RPR and in-hospital mortality risk in patients with ALC, both with and without severe liver disease, was initially examined using Kaplan-Meier (KM) curves. Subsequently, restricted cubic splines (RCS) and multivariable Cox propor

SUBMITTER: Dai J 

PROVIDER: S-EPMC12273180 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature