Prognostic value of carbohydrate antigen 125 combined with N-terminal pro B-type natriuretic peptide in patients with acute heart failure: a prospective cohort study in Vietnam.

ABSTRACT:

Background

Carbohydrate antigen 125 (CA125) is an emerging prognostic biomarker for acute heart failure (AHF). This study aimed to evaluate the prognostic utility of CA125 in combination with N-terminal pro-B-type natriuretic peptide (NT-proBNP) for predicting cardiovascular mortality, all-cause mortality, and a composite outcome of all-cause mortality or rehospitalization due to heart failure in patients with AHF.

Methods

This prospective observational study included 316 patients with AHF. Both CA125 and NT-proBNP levels were measured at the time of first admission. Mortality and rehospitalization due to heart failure were recorded over a 12-month follow-up period.

Results

During the follow-up period, 38 patients (12.0%) died from cardiovascular disease, 81 patients

SUBMITTER: Truong CM 

PROVIDER: S-EPMC12273334 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature