Efficacy of repetitive transcranial magnetic stimulation in cognitive impairment of neurodegenerative diseases: a systematic review and meta-analysis.

ABSTRACT:

Objective

Currently, there is a lack of reliable evidence to prove the effectiveness of repetitive transcranial magnetic stimulation (rTMS) in the cognitive and emotional domains of neurodegenerative diseases (ND), leading to the absence of a unified and effective rTMS treatment protocol or stimulation targets. This systematic review and meta-analysis summarizes existing evidence to evaluate the efficacy of rTMS targeting the dorsolateral prefrontal cortex (DLPFC) and non-DLPFC in the cognitive and emotional aspects of ND.

Methods

For two common types of ND Alzheimer's disease (AD) and Parkinson's disease (PD), we included 17 relevant randomized controlled trials (RCTs) from five databases. Search terms included rTMS, Parkinson's disease, Alzheimer's disease, cognitive impai

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12273377 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature