Feasibility of Monte Carlo-based patient-specific quality assurance in 1.5 Tesla magnetic resonance-guided online adaptive radiotherapy: a multi-institutional study.

ABSTRACT:

Introduction

To evaluate the feasibility of Monte Carlo (MC)-based patient-specific quality assurance (PSQA) for MR-guided online adaptive radiotherapy and to explore the potential to eliminate the post-delivery measurement-based PSQA.

Material and methods

A total of 113 cases from two institutions, treated on MR-Linac machines, were included in the study. A customized GPU-accelerated, Monte Carlo-based secondary dose verification software (ART2Dose) was developed and integrated into the QA workflow, accounting for a 1.5 Tesla magnetic field. PSQA included ArcCheck (AC) delivery QA and online MC calculation-based QA. Reference plans underwent offline validation with AC and MC, while adapt-to-shape (ATS) plans were processed through MC and post-delivery QA. Gamma pass rates (

SUBMITTER: Li R 

PROVIDER: S-EPMC12273433 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature