Comparative transcriptome analysis of bovine blastocysts reveals specific effects of the oocyte source and the environments during maturation and early embryo development.

ABSTRACT:

Background

Although differences between in vivo and in vitro derived bovine blastocysts in terms of global gene expression profiles have been reported, comparative transcriptome analyses specifically addressing the sustained impact of the oocyte source or the in vitro culture environments during maturation and post-maturation period are remain limited. Therefore, the present study aimed to investigate the specific impacts of oocyte origin and the culture environment during and after maturation on the gene expression signature at blastocyst stage. To achieve this, we utilized our recently developed technique that enables intrafollicular transfer of immature and matured slaughterhouse-derived oocytes into dominant or preovulatory follicles.

Results

The presents study identifie

SUBMITTER: Rahman MB 

PROVIDER: S-EPMC12273470 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature