Early MRI Blood Volume Changes in Constrictor Muscles Correlate With Postradiation Dysphagia.

ABSTRACT:

Purpose

Predicting individual patient sensitivity to radiation therapy (RT) for tumor control or normal tissue toxicity is necessary to individualize treatment planning. In head and neck cancer, radiation doses are limited by many nearby critical structures, including structures involved in swallowing. Previous efforts showed that imaging parameters correlate with RT dose; here, we investigate the role of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) blood volume (BV) changes in predicting dysphagia.

Methods and materials

This study included 32 patients with locally advanced oropharyngeal squamous cell carcinoma treated with definitive chemoradiation on an institutional protocol incorporating baseline and early midtreatment DCE-MRI. BV maps of the pharyngeal

SUBMITTER: Mierzwa ML 

PROVIDER: S-EPMC12273593 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature