AI-powered skin spectral imaging enables instant sepsis diagnosis and outcome prediction in critically ill patients.

ABSTRACT: With sepsis remaining a leading cause of mortality, early identification of patients with sepsis and those at high risk of death is a challenge of high socioeconomic importance. Given the potential of hyperspectral imaging (HSI) to monitor microcirculatory alterations, we propose a deep learning approach to automated sepsis diagnosis and mortality prediction using a single HSI cube acquired within seconds. In a prospective observational study, we collected HSI data from the palms and fingers of more than 480 intensive care unit patients. Neural networks applied to HSI measurements predicted sepsis and mortality with areas under the receiver operating characteristic curve (AUROCs) of 0.80 and 0.72, respectively. Performance improved substantially with additional clinical data, reaching AURO

SUBMITTER: Seidlitz S 

PROVIDER: S-EPMC12273750 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature