Effect of glycemic control and type of diabetes treatment on TB treatment outcomes among people with TB-diabetes: A systematic review (updated August 2024).

ABSTRACT:

Background

Stringent glycemic control and/or using insulin either as a replacement for or in addition to oral hypoglycemic agents (OHAs) has been recommended for people with tuberculosis and diabetes mellitus (TB-DM). This systematic review (PROSPERO 2016:CRD42016039101) analyses whether this improves TB treatment outcomes. This is an updated review (up to August 2024) of a previously published systematic review (1996 - April 2017).

Objectives

Among people with drug-susceptible TB-DM on anti-TB treatment, to determine the effect of i) glycemic control (stringent or less stringent) compared to poor glycemic control and ii) insulin (only or with OHAs) compared to 'OHAs only' on unfavorable TB treatment outcome(s) at the end of intensive phase and/ or end of TB treatment (minim

SUBMITTER: Shewade HD 

PROVIDER: S-EPMC12273911 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature