An artificial intelligence-based approach to identify volume status in patients with severe dengue using wearable PPG data.

ABSTRACT: Dengue shock syndrome (DSS) is a serious complication of dengue infection which occurs when critical plasma leakage results in haemodynamic shock. Treatment is challenging as fluid therapy must balance the risk of hypoperfusion with volume overload. In this study, we investigate the potential utility of wearable photoplethysmography (PPG) to determine volume status in DSS. In this prospective observational study, we enrolled 250 adults and children with a clinical diagnosis of dengue admitted to the Hospital for Tropical Diseases, Ho Chi Minh City. PPG monitoring using a wearable device was applied for a 24-hour period. Clinical events were then matched to the PPG data by date and time. We predefined two clinical states for comparison: (1) the 2-hour period before a shock event was an "emp

SUBMITTER: Lyle NN 

PROVIDER: S-EPMC12273927 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature