Effects of vitamin D on COVID-19 risk and hospitalisation in the UK biobank.

ABSTRACT:

Background

Vitamin D (VitD) plays an important role in immune modulation. VitD deficiency is associated with increased susceptibility to acute respiratory syndrome as observed in COVID-19. We evaluated potential associations between serum VitD levels and risk of COVID-19 infection and hospitalisation, within the overall and cancer populations.

Methods

We performed a nested case-control study within the UK biobank cohort, among all individuals with at least one serum VitD level measurement at baseline (2006-2010) and a COVID-19 polymerase chain reaction (PCR) results recorded, and individuals with previous cancer diagnosis. Binary multivariable logistic regression was performed to assess associations between VitD levels and risk of COVID-19 infection (positive PCR), and hospi

SUBMITTER: Monroy-Iglesias MJ 

PROVIDER: S-EPMC12273939 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature