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ABSTRACT: Background
Spinal manipulative therapy uses high-velocity low-amplitude (HVLA) thrusts which are clinically effective, but underlying mechanisms are still unknown.Objective
To summarize the evidence for biomechanical effects of HVLA thrusts in asymptomatic and symptomatic humans as well as for a possible link between biomechanical effects and clinical effectiveness.Study design
Systematic review of randomized controlled trials.Methods
An information specialist conducted systematic literature searches in six databases [Medline (OvidSP), Premedline (PubMed), CINAHL, EMBASE, Cochrane, and Biosis]. Studies were selected by two authors and classified using the revised Cochrane risk-of-bias tool for randomized trials (RoB 2). Results were qualitatively summarized
SUBMITTER: Langenfeld A
PROVIDER: S-EPMC12273944 | biostudies-literature | 2025
REPOSITORIES: biostudies-literature