Prediction Models for Gestational Diabetes Mellitus: Diagnostic Utility of Clinical and Biochemical Markers.

ABSTRACT:

Introduction

The use of oral glucose tolerance test (OGTT) is limited by an inconvenient procedure and poor reproducibility. This study aimed to develop and evaluate prediction models for gestational diabetes mellitus (GDM) diagnosis based on clinical and biochemical parameters.

Methods

An observational cross-sectional study was conducted among pregnant women aged 20-40 years in their second trimester (14-28 weeks) in Puducherry, South India, from May 2018 to March 2023. GDM was diagnosed according to the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria.

Results

The study included 234 normoglycemic women and 115 GDM women. Model 1 comprised the biomarkers: fasting plasma insulin, serum sex hormone binding globulin (SHBG), homeosta

SUBMITTER: Dinakaran A 

PROVIDER: S-EPMC12274042 | biostudies-literature | 2025 May-Jun

REPOSITORIES: biostudies-literature