Perioperative NT pro BNP can predict severe postoperative complications in elderly patients undergoing noncardiac surgery.

ABSTRACT: To develop a predictive model based on the perioperative plasma concentration of amino-terminal pro-brain natriuretic peptide (NT-pro BNP) in elderly patients to assess the risk of severe postoperative complications. Elderly patients (age ≥ 65 years) enrolled in this prospective observational study underwent general surgery. Plasma NT-Pro BNP concentration was measured before surgery and 2 h after surgery. Univariate and multivariate logistic regression analyses were used to identify the significant predictors. To evaluate the model performance, we applied the receiver operating characteristic (ROC) curve, Hosmer-Lemeshow test, and decision curve analysis (DCA) to evaluate the net clinical benefit. Prediction model was visualised by drawing nomogram and establishing web calculator. A total

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC12274438 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature