Timing of onset of persistent critical illness in Japan: a nationwide registry study.

ABSTRACT:

Background

Persistent critical illness (PerCI) occurs in patients whose ongoing ICU stay is no longer primarily driven by their presenting illness, but rather by new clinical instability. Studies in Western countries have found PerCI onset at 5-11 days, but timing in Japan or other Asian countries is unknown.

Methods

Using the Japanese Intensive Care Patient Database (JIPAD), PerCI onset was assessed by comparing the predictive ability of antecedent characteristics components (demographics, comorbidities) and acute illness components (physiological status at ICU admission) for in-hospital mortality, analyzed through multivariable logistic regression models among patients still in ICU from day 1 to day 28. The day when the Area Under the Receiver Operating Characteristic curv

SUBMITTER: Ohbe H 

PROVIDER: S-EPMC12274935 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature