Long-Term Outcome After Mustard Repair at Young Age: Longitudinal Follow-Up Into the Fifth Decade After Surgery.

ABSTRACT:

Background

Concerns remain regarding the high incidence of morbidity in transposition of the great arteries (TGA) patients who underwent Mustard repair.

Objectives

The purpose of this study was to evaluate the long-term outcome and quality of life of patients with TGA up to 48 years.

Methods

Single-center, longitudinal cohort study evaluating consecutive patients with TGA who underwent Mustard repair between 1973 and 1980 at young age with extensive cardiac and subjective quality of life evaluation every decade.

Results

Of the original cohort of 91 patients, 31 died and 2 underwent heart transplantation. Cumulative survival at 48 years was 61% (51% to 73%), with a shift in cause of death from sudden death to heart failure (HF) after 35 years of follow-up. Of th

SUBMITTER: Unluturk S 

PROVIDER: S-EPMC12275045 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature