Comparative transcriptomic analysis reveals breed-specific developmental characters of skin and feather follicles between Anser Cygnoides and Anser Anser.

ABSTRACT: Feather follicle development is essential for the phenotypic characteristics and economic value of domesticated geese. In this study, we conducted a comparative transcriptomic analysis to explore the breed-specific molecular mechanisms involved in feather follicle development in Zhedong white goose (Anser cygnoides) and Hungarian white goose (Anser anser) at five critical embryonic stages (E10, E13, E18, E23, and E28). A total of 19,622 differentially expressed genes (DEGs) were identified in geese feather follicles across the comparison groups, with significant enrichment in pathways associated with neuroactive ligand-receptor interaction, melanogenesis, tyrosine metabolism, metabolic pathways, PPAR, p53, VEGF, and Hedgehog signaling pathways. Thirty-six DEGs, such as SOX10, NEK3, PMEL, K

SUBMITTER: Mabrouk I 

PROVIDER: S-EPMC12275048 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature