Neuronal synchronization in <i>Dr</i> <i>oso</i> <i>phila</i>.

ABSTRACT: Collective rhythms are intrinsic to biological processes across temporal and spatial scales. In the brain, synchronized neuronal oscillations underlie collective rhythms essential for complex functions. Neuronal oscillations were reported in individual Drosophila neurons that underlie circadian and sleep behaviors. However, it is still unclear whether and how these participate in a collective rhythm. We perform whole-cell patch clamp recordings and demonstrate that membrane potential oscillations disappear after blocking nicotinic acetylcholine receptors. Perturbations to membrane potential do not change the phase of oscillation, further suggesting they depend on external inputs. We propose a theoretical description that accounts for experimental observations and predicts phase-lock

SUBMITTER: Fernandez-Chiappe F 

PROVIDER: S-EPMC12275062 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature