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Optimizing early hip maturation strategies in neonatal hip immaturity and dysplasia: a cohort study and network meta-analysis.


ABSTRACT:

Background

Early intervention is crucial for optimizing hip maturation in developmental dysplasia of the hip (DDH). This study evaluates the clinical effectiveness of various conservative management approaches.

Methods

We employed a dual-approach methodology combining original research with systematic evidence synthesis. First, we conducted a prospectively-designed retrospective cohort study from January 2021 to December 2023, comparing three treatment approaches in 103 hips: Pavlik harness (n = 35), double diapering (n = 39), and observation (n = 29), with 12-month follow-up. Second, we performed a network meta-analysis (NMA) registered in PROSPERO (CRD42024591239) to synthesize broader evidence on treatment effectiveness. We systematically searched MEDLINE, Embase, Scopus,

SUBMITTER: Su YC 

PROVIDER: S-EPMC12275155 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature