Septic arthritis score (SAS) - a novel clinical prediction model for the probability of septic arthritis in the adult native knee.

ABSTRACT:

Background

Patients presenting with an acutely painful swollen joint represent a diagnostic challenge. We aimed to develop a clinical prediction model for septic arthritis (SA) in the adult native knee.

Methods

We screened all synovial cultures in south Sweden in 2020 and 2021. We included cultures taken in the emergency department from adults' native knees where SA was considered a differential diagnosis based on medical chart review. We developed a prediction model using logistic regression and performed internal validation using bootstrapping. We present a nomogram and an online calculator ( http://sascore.org ) for individual risk estimation, net benefit compared to usual care and treatment threshold recommendations.

Results

A total of 668 patients were included f

SUBMITTER: Tverring J 

PROVIDER: S-EPMC12275251 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature