Long-term clinical sequelae among Sudan ebolavirus disease survivors 2 years post-infection: a matched cohort study.

ABSTRACT:

Background

The long-term health effects of ebolavirus disease (EVD) caused by the Sudan ebolavirus (SUDV) strain remain poorly characterized. Here, we assessed the nature, frequency, and persistence of post-EVD clinical symptoms among SUDV survivors 2 years after infection by comparing them with matched community controls.

Methods

The primary objective was determining the prevalence of clinical symptoms over the 24-month period. Using a prospective matched cohort approach, 87 laboratory-confirmed SUDV survivors from the 2022-2023 Ugandan outbreak and 176 age-, sex- and village-matched controls were followed at 3, 9, 12, 15 and 24 months. Symptom data were collected through structured interviews and targeted clinical examinations. A secondary objective was investigating the d

SUBMITTER: Muwonge H 

PROVIDER: S-EPMC12275283 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature