Pagetoid squamous cell carcinoma in situ (Pagetoid bowen's disease) of the nipple in an older male patient: a case report and literature review.

ABSTRACT:

Background

Pagetoid Bowen's disease (PBD) is a rare histological type of skin squamous cell carcinoma in situ. Due to its atypical pathological changes, it is often misdiagnosed and missed in clinical practice, making it difficult to diagnose. This is a rare report of unilateral nipple area PBD in an older male patient, providing insights into the diagnosis and treatment planning of PBD.

Case presentation

Here, we report the case of a 65-year-old Asian man with skin manifestations, such as erythema, scaling, erosion, and exudation of the left nipple. He had been treated for eczema for a long time without improvement, and his condition had recurred and worsened. Histopathological examination revealed scattered Pagetoid cell nests in the epidermis, an atypical manifestation of

SUBMITTER: Chen X 

PROVIDER: S-EPMC12275371 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature