Micronutrient Deficiency and Its Potential Role in Delirium Onset in Older Adults: A Systematic Review.

ABSTRACT:

Background and objectives

One of the pathogenetic hypotheses of delirium is the "neuroinflammatory theory" with consequent neurotoxicity of brain connectivity networks. Micronutrients may play a significant role in the prevention of neuroinflammation. This systematic review addresses the role of micronutrients in the development of delirium in older populations.

Methods

The EBSCO, Cochrane, PubMed, and Web of Science databases were searched for articles on delirium and micronutrients. The methodological quality of the studies included in the review was evaluated with the Newcastle-Ottawa Scales for observational studies and for case-control studies.

Results

1326 papers were identified from the searches, 7 of which met the inclusion criteria (see section 2.3). All the

SUBMITTER: Ceolin C 

PROVIDER: S-EPMC12275627 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature