Psoas and Paraspinous Muscle Measurements on Computed Tomography Predict Mortality in European Americans with Type 2 Diabetes Mellitus.

ABSTRACT:

Background

Appendicular skeletal muscle mass index and muscle attenuation (density) are negatively associated with mortality in European-derived populations.

Objectives

The present analyses assessed association between axial skeletal muscle density and muscle index with mortality in European Americans with type 2 diabetes mellitus (T2D).

Design

Single-center observational study.

Setting

Diabetes Heart Study.

Participants

839 European Americans with T2D.

Methods

Computed tomography-measured psoas and paraspinous muscle mass index (cross sectional area/height2) and radiographic density (Hounsfield Units) were assessed in all participants. A Cox proportional hazards model was computed. The fully-adjusted model included covariates age, sex, body mass

SUBMITTER: Tucker BM 

PROVIDER: S-EPMC12275710 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature