Reproductive factors and risk of physical frailty among Chinese women living in Singapore.

ABSTRACT:

Setting

Although age at menopause has been linked to higher risk of physical frailty in later life, little is known about other reproductive factors.

Objectives

Our study aimed to investigate the associations between 1) age at menarche, 2) age at natural menopause, 3) duration of reproductive period, 4) number of children, 5) use of oral contraceptives (OCP), and 6) use of hormone replacement therapy (HRT) with the risk of physical frailty in late life.

Design

We used data from 5934 women of the Singapore Chinese Health Study who experienced natural menopause, and participated in the third follow-up interviews when physical frailty was assessed. Logistic regression was used to evaluate association of reproductive factors evaluated during baseline and prior follow-up i

SUBMITTER: Ho VWT 

PROVIDER: S-EPMC12275779 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature