Global, Regional, and National Trends in the Burden of Anxiety Disorders From 1992 to 2021: An Age-Period-Cohort Analysis Based on the Global Burden of Disease Study 2021.

ABSTRACT: Background: Anxiety disorders pose a considerable global health challenge, ranking as the most prevalent type of mental illness. This study delineates the trends in incidence, prevalence, and years lived with disability (YLDs) for anxiety disorders at global, regional, and national levels between 1992 and 2021, with an emphasis on the independent effects of age, period, and birth cohort. Methods: Incidence, prevalence, and YLDs were selected as burden indicators of anxiety disorders, following the standardized methodologies of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021, with data presented as numerical counts and age-standardized rates (ASRs) per 100,000 population. An age-period-cohort (APC) model was applied to estimate the overall annual per

SUBMITTER: Zhou J 

PROVIDER: S-EPMC12276053 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature