Impact of anastomotic technique and norepinephrine on microcirculation in colorectal surgery: findings from a porcine model using laser speckle contrast imaging.

ABSTRACT:

Background

Proper intestinal anastomosis healing in colorectal surgery relies on optimal microcirculation, with surgeons choosing between the hand-sewn and stapled techniques. However, the impact of these methods on the microcirculation remains unclear. This study used laser speckle contrast imaging (LSCI) to objectively assess the impact of hand-sewn and stapled techniques on microcirculation in a porcine model during open surgery and examined microcirculatory changes during hypotension and norepinephrine (NE) correction.

Methods

Ten healthy female pigs underwent midline laparotomy, with one hand-sewn and one stapled anastomosis in both the small intestine and colon. LSCI measurements were obtained before creation (baseline), immediately after anastomosis (T₀), a

SUBMITTER: Paramasivam R 

PROVIDER: S-EPMC12276112 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature