Increased Glycemic Variability in Patients With Chronic Pancreatitis and Diabetes Compared to Type 2 Diabetes.

ABSTRACT:

Background

Glycemic variability in diabetes secondary to pancreatic diseases (pancreatic diabetes) remains unclear. We compared glycemic control and variability in patients with pancreatic diabetes and a matched group of individuals with type 2 diabetes using continuous glucose monitoring (CGM).

Methods

We included 30 patients with chronic pancreatitis and insulin-treated secondary diabetes and 30 individuals with insulin-treated type 2 diabetes (matched on HbA1c, age, and sex). Participants wore a blinded CGM for 20±2 days. Glycemic variability was assessed using coefficient of variation (CV), standard deviation (SD), mean amplitude of glycemic excursions (MAGE), and continuous overall net glycemic action (CONGA) at 1 and 2-hour intervals. Glycemic control was evaluated bas

SUBMITTER: Davidsen L 

PROVIDER: S-EPMC12276207 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature